PUBLISHED ABSTRACTS (n=80)
1. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Rôle de la Chromogranine A sur les effets moteurs et nociceptifs induits par l’acide acétique. Gastroentérologie clinique & biologique 2002 ; 26, HS1 0399–8320
2. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Effect of a synthetic fragment of Chromogranin on human colon motility. An in-vitro study. Gastroenterology 2002; 122 (4): A319
3. Ghia JE, Pradaud I*, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Peripheral anti-nociceptive and pro-nociceptive effects of Chromogranin A-derived fragments in visceral pain model in rats. Gastroenterology 2002; 122 (4): A412
4. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Modulation of acetic acid application on colonic motility in vitro by a synthetic fragment of Chromogranin A (CgA 4–16). Neurogastroenterology and Motility 2003; 15 (5): 53; 65
5. Ghia JE, Bernardin AL*, Aunis D, Angel F. Antimicrobial peptides modulate nociception in rats. Neurogastroenterology and Motility 2003; 15 (5): 61, 63
6. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Effect of a synthetic fragment of vasostatin, 47–66, on nociception and on in vitro colonic motility in rats. Neurogastroenterology and Motility 2003; 15 (5): 61, 66
7. Ghia JE, Blennerhassett P*, Verdu E, Ondiveeran KH, Collins SM. Vagal anti-inflammatory pathway in Dextran Sodium Sulfate colitis. Neurogastroenterology and Motility 2005; 17 (2): 48, 165
8. Angel F, Ghia JE, Bernardin AL*. Effects of antimicrobial peptides on inflammatory pain and colonic motility in rats. Neurogastroenterology and Motility 2005; 17 (2): 52, 179
9. Ghia JE, Blennerhassett P*, Verdu E, Kumar H, Collins SM. Tonic inhibitory influence of the vagus in experimental colitis. Gastroenterology 2005; 128 (4): A40, 297
10. Ghia JE, Blennerhassett P*, Ondiveeran KH, Verdu EF, Collins SM. The vagus nerve: A tonic inhibitory influence in a murine model of inflammatory bowel disease. Inflammatory Bowel Diseases 2006; 12 (2): S22
11. Ghia JE, Blennerhassett P*, Verdu EF, Collins SM. Tonic inhibitory influence of the vagus in chronic experimental colitis. Gastroenterology 2006; 130 (4): A545, T1705
12. Ghia JE, Blennerhassett P*, Collins SM. Attenuation of colitis by tricyclic anti-depressant is mediated via the vagus nerve. Gastroenterology 2007; 132 (4): A22, 116
13. Ghia JE, Blennerhassett P*, Collins SM. Vagal integrity and experimental colitis. The Canadian Journal of Gastroenterology 2007; 21 (supA): 99
14. Ghia JE, Blennerhassett P*, Park AJ*, Deng Y*, Cornell R* and Collins SM. Critical role of the alpha-7nicotinic acetylcholine receptor in the development of colitis. The Canadian Journal of Gastroenterology 2008; 22 (supA): 180A, 348
15. Ghia JE, Wang H*, Haq N, Deng Y*, El-Sharkawy RT, Velcich A and Khan WI. MUC 2 deficiency interfered in host defense against nematode infection. The Canadian Journal of Gastroenterology 2008; 22 (supA): 83A, 33
16. Ghia JE, Blennerhassett P* and Collins SM. Depression reactivates inflammatory bowel disease in mice. Gastroenterology 2008; 134 (4): A158, 698
17. Ghia JE, Wang H*, Li N*, Deng Y*, El-Sharkawy RT, Cote F, Mallet J and Khan WI. An essential role of 5-HT in pathogenesis of experimental colitis. Gastroenterology 2008; 134 (4): A218, S1284
18. Ghia JE, Blennerhassett P*, Park AJ*, Deng Y*, Cornell R* and Collins SM. Critical role of the alpha-7nicotinic acetylcholine receptor in the development of colitis. Gastroenterology 2008; 134 (4): A158, 1057
19. Ghia JE, Blennerhassett P*, Deng Y*, Khan WI and Collins SM. Role of the macrophage in depression-induced reactivation of experimental colitis. The Canadian Journal of Gastroenterology 2009; 23 (supA): 83A, 254
20. Park AJ*, Metz-Boutigue MH, Collins SM and Ghia JE. Inhibitory influence of Catestatin a Chromogranin A-derived peptide in experimental colitis. The Canadian Journal of Gastroenterology 2009; 23 (supA): 83A, 158
21. Ghia JE, Li N*, Wang H*, Côté F, El-Sharkawy R, Mallet J, Khan WI. Role of serotonin in immune activation and inflammation in experimental colitis. Gastroenterology 2009; 136 (5): M1624, A397
22. Wang H*, Ghia JE*, Hirotada A, Motomura Y, Côté F, Mallet J, Khan WI. Role of enterochromaffin cells in regulation of gut inflammation and host defense in enteric infection. Gastroenterology 2009; 136 (5): S1690, A271
23. Wang H*, Bogunovic M, Ghia JE, Hirotada A, McClemens J*, Jordana M, Mayer L, Khan WI. IL-13 plays a critical role in development of enterochromaffin cell hyperplasia and production of serotonin.Gastroenterology 2009; 136 (5): S1616, A235
24. Ghia JE, Blennerhassett P*, Khan WI and Collins SM. The adoptive transfer of susceptibility to colitis by macrophages from mice with depression-like behavior. The Canadian Journal of Gastroenterology 2010; 24 (supA): 76A, A34
25. McClemens J*, Wang H*, Forsythe P, Ghia JE, Bienenstock and Khan WI. Probiotic treatment up regulates goblet cell hyperplasia and promotes host defense in enteric parasite infection. The Canadian Journal of Gastroenterology 2010; 24 (supA): 113A, A138
26. Ghia JE, Blennerhassett P, Khan WI and Collins SM. Adoptive transfer of macrophage from mice with depression-like behavior confers susceptibility to colitis in naive mice. Gastroenterology 2010; 138 (5): T2052, S621
27. McClemens J*, Wang H*, Forsythe P, Ghia JE, Bienenstock and Khan WI. Treatment with Probiotic Bacteria During Enteric Parasite Infection Upregulates Goblet Cell Hyperplasia and Promotes Host Defense. Gastroenterology 2010; 138 (5): T2037, S618
28. Ghia JE, Denou E, Wang H*, Deng Y*, McClemens J*, Côté F, Collins S.M., Khan W.I. 5-HT plays an important role in regulation of composition of gut microbiota in the context of experimental colitis. Neurogastroenterology and Motility 2010; 22 (Sp1): 68, 43
29. Shajib M*, Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Jordona M, Denburg J, Khan W.I. Role of Interleukin-13 in reduced production of 5-HT in the gut and severity of colitis. The Canadian Journal of Gastroenterology 2011; 25 (supA): 132A, A198
30. Shajib M*, Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Jordona M, Denburg J, Khan W.I. Influence of interleukin-13 in 5-HT synthesis and severity of experimental colitis.Gastroenterology 2011; 140 (5): 105, S26
31. Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Khan W.I. Inhibition of 5-HT signaling by blocking 5-HT7 receptor functions alleviates colitis. Gastroenterology 2011; 140 (5): 104, S26
32. Kim JJ*, Bridle B, Ghia JE, Wang H*, Wan Y, Hedlund P, Khan W.I. Novel strategy to reduce the severity of intestinal inflammation by disrupting 5-HT7 receptor signaling. The Canadian Journal of Gastroenterology 2012; 26 (SupA): 76A, A12
33. Ji H*, Labis B*, Pavlov V, Tracey K, Ghia JE Pharmacological central activation of the vagus nerve reduces experimental colitis. Gastroenterology 2012; 142 (5): 876, 151-S152
34. Kim JJ*, Wang H*, Zaman T, Hedlund PB, Ghia JE, Khan WI, Role of 5-HT7 in intestinal muscle function and host defense in an enteric parasitic infection. Neurogastroenterology and Motility 2012; 24 (Sp2): 63, 71
35. Ji H*, Labis B*, Rabbi M*, Pavlov V, Tracey K, Ghia JE Attenuation of colitis by acetylcholinesterase inhibitor is mediated via the vagus nerve and the dendritic cells Neurogastroenterology and Motility 2012; 24 (Sp2): 140, 334
36. Rabbi M*, Ji H*, Metz-Boutigue MH, Ghia JE Inhibitory influence of cateslytin a Chromogranin-A derived peptide in experimental colitis. The Canadian Journal of Gastroenterology 2013; 27 (SupA): 121A, A146
37. Ji H*, Rabbi M*, Labis B*, Pavlov V, Tracey K, Ghia JE Central Muscarinic 1 receptor activation reduces experimental colitis via the vagus nerve. The Canadian Journal of Gastroenterology 2013; 27 (SupA): 144A, A210
38. Ji H*, Rabbi M*, Labis B*, Pavlov V, Tracey K, Ghia JE Central muscarinic 1 acetylcholine receptor activation reduces the severity of experimental colitis via the splenic nerve and the spleen.Gastroenterology 2013; 144 (5): S66
39. Rabbi M*, Ji H*, Odigie A, Pavlov VA, Tracey KJ & Ghia JE Central muscarinic 1 acetylcholine receptor activation reduces the severity of experimental colitis via the vagus nerve and the splenic dendritic cells. Autonomic Neuroscience, Basic and Clinical 2013; 177 (2), 316–317
40. Munyaka PM*, Hartman RJ, Rodriguez-Lecompte JC, Ghia JE, Krause DO, and Khafipour E. Gut microbiome profile of early weaned piglets in response to crowding stress, Escherichia coli K88+ challenge, and anti-E. coli K88 probiotics. J. Anim. Sci. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1
41. Rabbi M*, Ji H*, Metz-Boutigue MH, Ghia JE Human Catestatin and its derived peptides protect mice from experimental colitis. The Canadian Journal of Gastroenterology 2014 (SupA): A144
42. Munyaka PM*, Ghia JE, Bernstein CN, Khafipour E. AIEC Pathobiont and Carrageenan Gum Alter Gut Microbiome Profile in a Pig Model of Inflammatory Bowel Disease.
43. Munyaka PM*, Ghia JE, Bernstein CN, Khafipour E. Intestinal microbiome profile in a piglet model of inflammatory bowel disease: The impact of prebiotic (resistant starch) and Escherichia coli-derived probiotics.
44. Khafipour E, Munyaka PM*, Bernstein CN, Ghia JE. Therapeutic role of prebiotic (resistant starch) and Escherichia coli-derived probiotics in piglets infected with adherent invasive Escherichia coli (AIEC) UM146: A model of inflammatory bowel disease.
45. Munyaka PM*, Rabbi M*, Tracey KJ, Pavlov VA, Ghia JE. Central muscarinic cholinergic activation alters splenic dendritic cell activation in experimental colitis. Neurogastroenterology and Motility 2014; 26 (Sp1): 13, PP009
46. Munyaka PM*, Rabbi M*, Tracey KJ, Pavlov VA, Ghia JE. Central muscarinic cholinergic activation alters interaction between splenic dendritic cell and CD 4+CD25- T cells in experimental colitis. United European Gastroenterology Journal 2014, 2 (1 S), OP273
47. Khafipour A*, Munyaka PM*, Wang H*, Eissa N*, Bernstein CN, Ghia JE. Denosumab: a monoclonal antibody to Receptor Activator of Nuclear factor-Kappa B ligand (RANKL) decreases experimental colitis. Gastroenterology 2015, 148, 4, S688-689
48. Heydarpour P, Rahimian R, Fakhfouri G, Khoshkish S, Salehi-Sadaghiani M Fakhraei N, Abbasi A, Heydarpour F, Dehpour AR, Ghia JE. Behavioral despair associated with a mouse model of inflammatory bowel disease: role of the nitric oxide pathway. Gastroenterology 2015, 148, 4, S383-384
49. Munyaka PM*, Khafipour A*, Wang H*, Eissa N*, Khafipour E*, Ghia JE. Prenatal antibiotic treatment increases offspring’s susceptibility to experimental colitis: a role for the microbiota. Gastroenterology 2015, 148, 4, S708
50. Bernstein CN, Banerjee A, Targownik LE, Singh H, Ghia JE, Burchill C, Chateau D, Roos LL. Caesarian section is not a risk factor for the development of IBD: A population-based analysis.Gastroenterology 2015, 148, 4, S465
51. Munyaka PM*, Khafipour A*, Wang H*, Eissa N*, Khafipour E, Ghia JE. Perinatal antibiotic treatment alters offspring gut microbial profile predisposing to experimental colitis. United European Gastroenterol. J. 2015 3 (5 suppl.): A497 P200
52. Eissa N*, Wang H*, Munyaka PM*, Khafipour A*, Bernstein CN, Ghia JE. Chromogranin-A regulates anti-inflammatory markers in the context of experimental colitis and human rectal samples. United European Gastroenterol. J. 2015 3 (5 suppl.): A142, OP443
53. Eissa N*, Wang H*, Munyaka PM*, Khafipour A*, Ghia JE. Chromogranin-A regulates P53-upregulated modulator of apoptosis (PUMA) and B-cell lymphoma-2 (BCL-2) pro-apoptotic mediators in experimental colitis. United European Gastroenterol. J. 2015 3 (5 suppl.): A586, P1513
54. Munyaka P*, Bernstein CN, Khafipour E, Ghia JE. Antepartum antibiotic treatment increases offspring susceptibility to experimental colitis: a role of the gut microbiota. Microbiome
55. Rabbi MF*, Munyaka PM*, Eissa N*, Khafipour A*, Khafipour E, Ghia JE. Human Catestatin treatment results in gut microbiota dysbiosis in mice. The Canadian Journal of Gastroenterology 2016 (Sup A): A129
56. Khafipour A*, Munyaka PM*, Rabbi MF*, Eissa N*, Khafipour E, Ghia JE. Acute 2,4 dinitrobenszensulfonic acid (DNBS)-induced colitis results in gut microbiota dysbiosis in mice. The Canadian Journal of Gastroenterology 2016 (Sup A): A130
57. Eissa N*, Rabbi MF*, Mesgna R*, Khafipour A*, Bernstein CN, Ghia JE. Critical role of Chromogranin-A in the context of colorectal inflammation: human and animal studies. The Canadian Journal of Gastroenterology 2016 (Sup A): A255
58. Denou E, Ghia JE, Wang H*, Kim JJ*, Shajib M*, Shah M, Surette M, Collins SM, Khan W.I. The serotoninergic endocrine-gut microbiota axis in experimental colitis. The Canadian Journal of Gastroenterology 2016 (Sup A): A123
59. Rabbi MF*, Eissa N*, Munyaka PM*, Khafipour A*, Khafipour E, Ghia JE. Human Catestatin represses reactivation of intestinal inflammation in a murine model of colitis through the M1 macrophages and not the gut microbiota. Gastroenterology 2016, 150, 4, S969
60. Wang H*, Han B, Han D, Wu F, Liu K, Li H, Li C, Zhao S, Sun Q, Ma L, Shan X, Ghia JE. Increased serum lipopolysaccharides is associated with tumor necrosis factor-alpha and formation of β amyloid protein in patients with Alzheimer’s disease. Gastroenterology 2016, 150, 4, S523
61. Eissa N*, Rabbi MF*, Mesgna R*, Khafipour A*, Bernstein CN, Ghia JE. Critical role of Chromogranin-A on macrophage intrinsic apoptotic pathway in colitis: human and animal studies. Gastroenterology 2016, 150, 4, S819
62. Eissa N*, Hussein H*, Ghia JE. Stability of reference genes for messenger RNA quantification by real-time PCR in mouse dextran sodium sulfate experimental colitis. Gastroenterology 2016, 150, 4, S955-956
63. Munyaka PM*, Rabbi MF*, Khafipour A*, Khafipour E, Ghia JE. Acute dextran sulfate sodium (DSS)-induced colitis promotes gut microbial dysbiosis and functional microbial changes in mice. Gastroenterology 2016, 150, 4, S465
64. Wang H*, Han B, Han D, Wu F, Liu K, Li H, Li C, Sun Q, Ma L, Ghia JE. Increased serum lipopolysaccharides is associated with tumor necrosis factor-alpha and formation of β amyloid protein in a rat model of Alzheimer’s disease. Neurogastroenterology and Motility 2016; 28 (Sp1): 90, 72
65. Eissa N*, Rabbi MF*, Bernstein CN, Ghia JE. Chromofungin & pancreastatin co-regulate migration and functional plasticity of murine peritoneal macrophages. Neurogastroenterology and Motility 2016; 28 (Sp1): 353, 143–144
66. Eissa N*, Rabbi MF*, Bernstein CN, Ghia JE. Chromofungin, a Chromogranin-A derived peptide, regulates macrophage plasticity in an experimental model of colitis. United European Gastroenterol. J. 2016 4 (5 suppl.): A139, OP357
67. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. Semaphorin3E (Sema3E) regulates intestinal inflammation through the modulation of dendritic cells functions. The Canadian Journal of Gastroenterology 2017, in press
68. Eissa N*, Kermarrec L*, Bernstein CN, Ghia JE. Pancreastatin (PTS) exacerbates colonic inflammation. The Canadian Journal of Gastroenterology 2017, in press
69. Eissa N*, Kermarrec L*, Metz-Boutigue MH, Hendy G, Bernstein CN, Ghia JE. Chromofungin treatment promotes alternatively activated macrophages, suppresses classically activated macrophages and improves epithelial cell functions during colitis. Gastroenterology 2017, 152, 5, S143
70. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. A down regulation of Semaphorin3E (Sema3E) in active ulcerative colitis and experimental colitis is associated to an alteration of splenic CD11C+ T-cell priming. Gastroenterology 2017, 152, 5, S144
71. Eissa N*, Kermarrec L*, Bernstein CN, Ghia JE. Chromofungin, CgA47-66 Derived Peptide, Promotes Alternatively Activated Macrophages, Suppresses Classically Activated Macrophages and Improves Epithelial Barrier Functions During Colitis. United European Gastroenterol. J. 2017 5 (5 suppl.): A115, OP270
72. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. Semaphorin 3E plays a role in tight junction epithelial barrier maintenance in patients with active ulcerative colitis. United European Gastroenterol. J. 2017 5 (5 suppl.): A129, OP302
73. Eissa N*, Hussein H*, Kermarrec L, Bernstein CN, Ghia JE. Chromofungin, Chromogranin-A Contributes to the Intestinal Inflammation by Mediating the Functions of Alternatively Activated Macrophages and Intestinal Epithelial Cells
Gastroenterology 2018, 154, 6, S922
74. Elgazzar O, Eissa N, Kermarrec L, Kirouac G, Ghia JE. Irritable Bowel Syndrome-Related Neurotransmitters Transporters and Metabolism Gene Expression but Not Gut Microbiota are altered in a Rat Model of Post-Traumatic Stress Disorder Neurogastroenterology and Motility 2018; in press
75. Eissa N*, Mesgna R, Hendy G, Bernstein CN, Ghia JE. Catestatin ameliorates intestinal inflammation by orchestrating tight junction dynamics via STAT3-dependent pathway. United European Gastroenterol. J. 2018 6 (5 suppl.): Axx, OP270
76. Diarra A*, Eissa N*, Kapoor K*, Ghia JE. Regulation of endoplasmic reticulum stress/p53-apopotitic pathways by chromofungin in the context of experimental colitis. Journal of Canadian Association of Gastroenterology 2019, 2 (2 suppl.): 203-204 A102
77. Eissa N*, Diarra A*, Bernstein CN, Ghia JE. Chromogranin-A Regulates Indirectly Epithelial Repair via the alternatively activated macrophages in colonic inflammatory states. Journal of Canadian Association of Gastroenterology 2019, 2 (2 suppl.): 86-87 A43
78. Eissa N*, Hussein H*, Kermarrec L, Bernstein CN, Ghia JE. Semaphorin -3E regulates apoptosis during the development of colonic inflammation Gastroenterology 2019, in press
76. Diarra A*, Eissa N*, Kapoor K*, Ghia JE. Chromofungin protects against DSS-induced colitis by regulating P-53 apoptotic pathway. Journal of Canadian Association of Gastroenterology 2020, 3 (1 suppl.): 84-85 A212
80. Eissa N*, Diarra A*, Hussein H*, Elgazzar O*, Bernstein CN, Ghia JE. The Lack of Chromogranin-A Modifies the Gut Microbiota composition and Regulates Experimental Colonic Inflammation Journal of Canadian Association of Gastroenterology 3, (1 suppl.): 137-138 A260
1. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Rôle de la Chromogranine A sur les effets moteurs et nociceptifs induits par l’acide acétique. Gastroentérologie clinique & biologique 2002 ; 26, HS1 0399–8320
2. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Effect of a synthetic fragment of Chromogranin on human colon motility. An in-vitro study. Gastroenterology 2002; 122 (4): A319
3. Ghia JE, Pradaud I*, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Peripheral anti-nociceptive and pro-nociceptive effects of Chromogranin A-derived fragments in visceral pain model in rats. Gastroenterology 2002; 122 (4): A412
4. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Modulation of acetic acid application on colonic motility in vitro by a synthetic fragment of Chromogranin A (CgA 4–16). Neurogastroenterology and Motility 2003; 15 (5): 53; 65
5. Ghia JE, Bernardin AL*, Aunis D, Angel F. Antimicrobial peptides modulate nociception in rats. Neurogastroenterology and Motility 2003; 15 (5): 61, 63
6. Ghia JE, Crenner F, Metz-Boutigue MH, Aunis D, Angel F. Effect of a synthetic fragment of vasostatin, 47–66, on nociception and on in vitro colonic motility in rats. Neurogastroenterology and Motility 2003; 15 (5): 61, 66
7. Ghia JE, Blennerhassett P*, Verdu E, Ondiveeran KH, Collins SM. Vagal anti-inflammatory pathway in Dextran Sodium Sulfate colitis. Neurogastroenterology and Motility 2005; 17 (2): 48, 165
8. Angel F, Ghia JE, Bernardin AL*. Effects of antimicrobial peptides on inflammatory pain and colonic motility in rats. Neurogastroenterology and Motility 2005; 17 (2): 52, 179
9. Ghia JE, Blennerhassett P*, Verdu E, Kumar H, Collins SM. Tonic inhibitory influence of the vagus in experimental colitis. Gastroenterology 2005; 128 (4): A40, 297
10. Ghia JE, Blennerhassett P*, Ondiveeran KH, Verdu EF, Collins SM. The vagus nerve: A tonic inhibitory influence in a murine model of inflammatory bowel disease. Inflammatory Bowel Diseases 2006; 12 (2): S22
11. Ghia JE, Blennerhassett P*, Verdu EF, Collins SM. Tonic inhibitory influence of the vagus in chronic experimental colitis. Gastroenterology 2006; 130 (4): A545, T1705
12. Ghia JE, Blennerhassett P*, Collins SM. Attenuation of colitis by tricyclic anti-depressant is mediated via the vagus nerve. Gastroenterology 2007; 132 (4): A22, 116
13. Ghia JE, Blennerhassett P*, Collins SM. Vagal integrity and experimental colitis. The Canadian Journal of Gastroenterology 2007; 21 (supA): 99
14. Ghia JE, Blennerhassett P*, Park AJ*, Deng Y*, Cornell R* and Collins SM. Critical role of the alpha-7nicotinic acetylcholine receptor in the development of colitis. The Canadian Journal of Gastroenterology 2008; 22 (supA): 180A, 348
15. Ghia JE, Wang H*, Haq N, Deng Y*, El-Sharkawy RT, Velcich A and Khan WI. MUC 2 deficiency interfered in host defense against nematode infection. The Canadian Journal of Gastroenterology 2008; 22 (supA): 83A, 33
16. Ghia JE, Blennerhassett P* and Collins SM. Depression reactivates inflammatory bowel disease in mice. Gastroenterology 2008; 134 (4): A158, 698
17. Ghia JE, Wang H*, Li N*, Deng Y*, El-Sharkawy RT, Cote F, Mallet J and Khan WI. An essential role of 5-HT in pathogenesis of experimental colitis. Gastroenterology 2008; 134 (4): A218, S1284
18. Ghia JE, Blennerhassett P*, Park AJ*, Deng Y*, Cornell R* and Collins SM. Critical role of the alpha-7nicotinic acetylcholine receptor in the development of colitis. Gastroenterology 2008; 134 (4): A158, 1057
19. Ghia JE, Blennerhassett P*, Deng Y*, Khan WI and Collins SM. Role of the macrophage in depression-induced reactivation of experimental colitis. The Canadian Journal of Gastroenterology 2009; 23 (supA): 83A, 254
20. Park AJ*, Metz-Boutigue MH, Collins SM and Ghia JE. Inhibitory influence of Catestatin a Chromogranin A-derived peptide in experimental colitis. The Canadian Journal of Gastroenterology 2009; 23 (supA): 83A, 158
21. Ghia JE, Li N*, Wang H*, Côté F, El-Sharkawy R, Mallet J, Khan WI. Role of serotonin in immune activation and inflammation in experimental colitis. Gastroenterology 2009; 136 (5): M1624, A397
22. Wang H*, Ghia JE*, Hirotada A, Motomura Y, Côté F, Mallet J, Khan WI. Role of enterochromaffin cells in regulation of gut inflammation and host defense in enteric infection. Gastroenterology 2009; 136 (5): S1690, A271
23. Wang H*, Bogunovic M, Ghia JE, Hirotada A, McClemens J*, Jordana M, Mayer L, Khan WI. IL-13 plays a critical role in development of enterochromaffin cell hyperplasia and production of serotonin.Gastroenterology 2009; 136 (5): S1616, A235
24. Ghia JE, Blennerhassett P*, Khan WI and Collins SM. The adoptive transfer of susceptibility to colitis by macrophages from mice with depression-like behavior. The Canadian Journal of Gastroenterology 2010; 24 (supA): 76A, A34
25. McClemens J*, Wang H*, Forsythe P, Ghia JE, Bienenstock and Khan WI. Probiotic treatment up regulates goblet cell hyperplasia and promotes host defense in enteric parasite infection. The Canadian Journal of Gastroenterology 2010; 24 (supA): 113A, A138
26. Ghia JE, Blennerhassett P, Khan WI and Collins SM. Adoptive transfer of macrophage from mice with depression-like behavior confers susceptibility to colitis in naive mice. Gastroenterology 2010; 138 (5): T2052, S621
27. McClemens J*, Wang H*, Forsythe P, Ghia JE, Bienenstock and Khan WI. Treatment with Probiotic Bacteria During Enteric Parasite Infection Upregulates Goblet Cell Hyperplasia and Promotes Host Defense. Gastroenterology 2010; 138 (5): T2037, S618
28. Ghia JE, Denou E, Wang H*, Deng Y*, McClemens J*, Côté F, Collins S.M., Khan W.I. 5-HT plays an important role in regulation of composition of gut microbiota in the context of experimental colitis. Neurogastroenterology and Motility 2010; 22 (Sp1): 68, 43
29. Shajib M*, Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Jordona M, Denburg J, Khan W.I. Role of Interleukin-13 in reduced production of 5-HT in the gut and severity of colitis. The Canadian Journal of Gastroenterology 2011; 25 (supA): 132A, A198
30. Shajib M*, Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Jordona M, Denburg J, Khan W.I. Influence of interleukin-13 in 5-HT synthesis and severity of experimental colitis.Gastroenterology 2011; 140 (5): 105, S26
31. Kim JJ*, Wang H*, Ghia JE, Collins M, McClemens J*, Khan W.I. Inhibition of 5-HT signaling by blocking 5-HT7 receptor functions alleviates colitis. Gastroenterology 2011; 140 (5): 104, S26
32. Kim JJ*, Bridle B, Ghia JE, Wang H*, Wan Y, Hedlund P, Khan W.I. Novel strategy to reduce the severity of intestinal inflammation by disrupting 5-HT7 receptor signaling. The Canadian Journal of Gastroenterology 2012; 26 (SupA): 76A, A12
33. Ji H*, Labis B*, Pavlov V, Tracey K, Ghia JE Pharmacological central activation of the vagus nerve reduces experimental colitis. Gastroenterology 2012; 142 (5): 876, 151-S152
34. Kim JJ*, Wang H*, Zaman T, Hedlund PB, Ghia JE, Khan WI, Role of 5-HT7 in intestinal muscle function and host defense in an enteric parasitic infection. Neurogastroenterology and Motility 2012; 24 (Sp2): 63, 71
35. Ji H*, Labis B*, Rabbi M*, Pavlov V, Tracey K, Ghia JE Attenuation of colitis by acetylcholinesterase inhibitor is mediated via the vagus nerve and the dendritic cells Neurogastroenterology and Motility 2012; 24 (Sp2): 140, 334
36. Rabbi M*, Ji H*, Metz-Boutigue MH, Ghia JE Inhibitory influence of cateslytin a Chromogranin-A derived peptide in experimental colitis. The Canadian Journal of Gastroenterology 2013; 27 (SupA): 121A, A146
37. Ji H*, Rabbi M*, Labis B*, Pavlov V, Tracey K, Ghia JE Central Muscarinic 1 receptor activation reduces experimental colitis via the vagus nerve. The Canadian Journal of Gastroenterology 2013; 27 (SupA): 144A, A210
38. Ji H*, Rabbi M*, Labis B*, Pavlov V, Tracey K, Ghia JE Central muscarinic 1 acetylcholine receptor activation reduces the severity of experimental colitis via the splenic nerve and the spleen.Gastroenterology 2013; 144 (5): S66
39. Rabbi M*, Ji H*, Odigie A, Pavlov VA, Tracey KJ & Ghia JE Central muscarinic 1 acetylcholine receptor activation reduces the severity of experimental colitis via the vagus nerve and the splenic dendritic cells. Autonomic Neuroscience, Basic and Clinical 2013; 177 (2), 316–317
40. Munyaka PM*, Hartman RJ, Rodriguez-Lecompte JC, Ghia JE, Krause DO, and Khafipour E. Gut microbiome profile of early weaned piglets in response to crowding stress, Escherichia coli K88+ challenge, and anti-E. coli K88 probiotics. J. Anim. Sci. 91, E-Suppl. 2/J. Dairy Sci. Vol. 96, E-Suppl. 1
41. Rabbi M*, Ji H*, Metz-Boutigue MH, Ghia JE Human Catestatin and its derived peptides protect mice from experimental colitis. The Canadian Journal of Gastroenterology 2014 (SupA): A144
42. Munyaka PM*, Ghia JE, Bernstein CN, Khafipour E. AIEC Pathobiont and Carrageenan Gum Alter Gut Microbiome Profile in a Pig Model of Inflammatory Bowel Disease.
43. Munyaka PM*, Ghia JE, Bernstein CN, Khafipour E. Intestinal microbiome profile in a piglet model of inflammatory bowel disease: The impact of prebiotic (resistant starch) and Escherichia coli-derived probiotics.
44. Khafipour E, Munyaka PM*, Bernstein CN, Ghia JE. Therapeutic role of prebiotic (resistant starch) and Escherichia coli-derived probiotics in piglets infected with adherent invasive Escherichia coli (AIEC) UM146: A model of inflammatory bowel disease.
45. Munyaka PM*, Rabbi M*, Tracey KJ, Pavlov VA, Ghia JE. Central muscarinic cholinergic activation alters splenic dendritic cell activation in experimental colitis. Neurogastroenterology and Motility 2014; 26 (Sp1): 13, PP009
46. Munyaka PM*, Rabbi M*, Tracey KJ, Pavlov VA, Ghia JE. Central muscarinic cholinergic activation alters interaction between splenic dendritic cell and CD 4+CD25- T cells in experimental colitis. United European Gastroenterology Journal 2014, 2 (1 S), OP273
47. Khafipour A*, Munyaka PM*, Wang H*, Eissa N*, Bernstein CN, Ghia JE. Denosumab: a monoclonal antibody to Receptor Activator of Nuclear factor-Kappa B ligand (RANKL) decreases experimental colitis. Gastroenterology 2015, 148, 4, S688-689
48. Heydarpour P, Rahimian R, Fakhfouri G, Khoshkish S, Salehi-Sadaghiani M Fakhraei N, Abbasi A, Heydarpour F, Dehpour AR, Ghia JE. Behavioral despair associated with a mouse model of inflammatory bowel disease: role of the nitric oxide pathway. Gastroenterology 2015, 148, 4, S383-384
49. Munyaka PM*, Khafipour A*, Wang H*, Eissa N*, Khafipour E*, Ghia JE. Prenatal antibiotic treatment increases offspring’s susceptibility to experimental colitis: a role for the microbiota. Gastroenterology 2015, 148, 4, S708
50. Bernstein CN, Banerjee A, Targownik LE, Singh H, Ghia JE, Burchill C, Chateau D, Roos LL. Caesarian section is not a risk factor for the development of IBD: A population-based analysis.Gastroenterology 2015, 148, 4, S465
51. Munyaka PM*, Khafipour A*, Wang H*, Eissa N*, Khafipour E, Ghia JE. Perinatal antibiotic treatment alters offspring gut microbial profile predisposing to experimental colitis. United European Gastroenterol. J. 2015 3 (5 suppl.): A497 P200
52. Eissa N*, Wang H*, Munyaka PM*, Khafipour A*, Bernstein CN, Ghia JE. Chromogranin-A regulates anti-inflammatory markers in the context of experimental colitis and human rectal samples. United European Gastroenterol. J. 2015 3 (5 suppl.): A142, OP443
53. Eissa N*, Wang H*, Munyaka PM*, Khafipour A*, Ghia JE. Chromogranin-A regulates P53-upregulated modulator of apoptosis (PUMA) and B-cell lymphoma-2 (BCL-2) pro-apoptotic mediators in experimental colitis. United European Gastroenterol. J. 2015 3 (5 suppl.): A586, P1513
54. Munyaka P*, Bernstein CN, Khafipour E, Ghia JE. Antepartum antibiotic treatment increases offspring susceptibility to experimental colitis: a role of the gut microbiota. Microbiome
55. Rabbi MF*, Munyaka PM*, Eissa N*, Khafipour A*, Khafipour E, Ghia JE. Human Catestatin treatment results in gut microbiota dysbiosis in mice. The Canadian Journal of Gastroenterology 2016 (Sup A): A129
56. Khafipour A*, Munyaka PM*, Rabbi MF*, Eissa N*, Khafipour E, Ghia JE. Acute 2,4 dinitrobenszensulfonic acid (DNBS)-induced colitis results in gut microbiota dysbiosis in mice. The Canadian Journal of Gastroenterology 2016 (Sup A): A130
57. Eissa N*, Rabbi MF*, Mesgna R*, Khafipour A*, Bernstein CN, Ghia JE. Critical role of Chromogranin-A in the context of colorectal inflammation: human and animal studies. The Canadian Journal of Gastroenterology 2016 (Sup A): A255
58. Denou E, Ghia JE, Wang H*, Kim JJ*, Shajib M*, Shah M, Surette M, Collins SM, Khan W.I. The serotoninergic endocrine-gut microbiota axis in experimental colitis. The Canadian Journal of Gastroenterology 2016 (Sup A): A123
59. Rabbi MF*, Eissa N*, Munyaka PM*, Khafipour A*, Khafipour E, Ghia JE. Human Catestatin represses reactivation of intestinal inflammation in a murine model of colitis through the M1 macrophages and not the gut microbiota. Gastroenterology 2016, 150, 4, S969
60. Wang H*, Han B, Han D, Wu F, Liu K, Li H, Li C, Zhao S, Sun Q, Ma L, Shan X, Ghia JE. Increased serum lipopolysaccharides is associated with tumor necrosis factor-alpha and formation of β amyloid protein in patients with Alzheimer’s disease. Gastroenterology 2016, 150, 4, S523
61. Eissa N*, Rabbi MF*, Mesgna R*, Khafipour A*, Bernstein CN, Ghia JE. Critical role of Chromogranin-A on macrophage intrinsic apoptotic pathway in colitis: human and animal studies. Gastroenterology 2016, 150, 4, S819
62. Eissa N*, Hussein H*, Ghia JE. Stability of reference genes for messenger RNA quantification by real-time PCR in mouse dextran sodium sulfate experimental colitis. Gastroenterology 2016, 150, 4, S955-956
63. Munyaka PM*, Rabbi MF*, Khafipour A*, Khafipour E, Ghia JE. Acute dextran sulfate sodium (DSS)-induced colitis promotes gut microbial dysbiosis and functional microbial changes in mice. Gastroenterology 2016, 150, 4, S465
64. Wang H*, Han B, Han D, Wu F, Liu K, Li H, Li C, Sun Q, Ma L, Ghia JE. Increased serum lipopolysaccharides is associated with tumor necrosis factor-alpha and formation of β amyloid protein in a rat model of Alzheimer’s disease. Neurogastroenterology and Motility 2016; 28 (Sp1): 90, 72
65. Eissa N*, Rabbi MF*, Bernstein CN, Ghia JE. Chromofungin & pancreastatin co-regulate migration and functional plasticity of murine peritoneal macrophages. Neurogastroenterology and Motility 2016; 28 (Sp1): 353, 143–144
66. Eissa N*, Rabbi MF*, Bernstein CN, Ghia JE. Chromofungin, a Chromogranin-A derived peptide, regulates macrophage plasticity in an experimental model of colitis. United European Gastroenterol. J. 2016 4 (5 suppl.): A139, OP357
67. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. Semaphorin3E (Sema3E) regulates intestinal inflammation through the modulation of dendritic cells functions. The Canadian Journal of Gastroenterology 2017, in press
68. Eissa N*, Kermarrec L*, Bernstein CN, Ghia JE. Pancreastatin (PTS) exacerbates colonic inflammation. The Canadian Journal of Gastroenterology 2017, in press
69. Eissa N*, Kermarrec L*, Metz-Boutigue MH, Hendy G, Bernstein CN, Ghia JE. Chromofungin treatment promotes alternatively activated macrophages, suppresses classically activated macrophages and improves epithelial cell functions during colitis. Gastroenterology 2017, 152, 5, S143
70. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. A down regulation of Semaphorin3E (Sema3E) in active ulcerative colitis and experimental colitis is associated to an alteration of splenic CD11C+ T-cell priming. Gastroenterology 2017, 152, 5, S144
71. Eissa N*, Kermarrec L*, Bernstein CN, Ghia JE. Chromofungin, CgA47-66 Derived Peptide, Promotes Alternatively Activated Macrophages, Suppresses Classically Activated Macrophages and Improves Epithelial Barrier Functions During Colitis. United European Gastroenterol. J. 2017 5 (5 suppl.): A115, OP270
72. Kermarrec L*, Eissa N*, Bernstein CN, Ghia JE. Semaphorin 3E plays a role in tight junction epithelial barrier maintenance in patients with active ulcerative colitis. United European Gastroenterol. J. 2017 5 (5 suppl.): A129, OP302
73. Eissa N*, Hussein H*, Kermarrec L, Bernstein CN, Ghia JE. Chromofungin, Chromogranin-A Contributes to the Intestinal Inflammation by Mediating the Functions of Alternatively Activated Macrophages and Intestinal Epithelial Cells
Gastroenterology 2018, 154, 6, S922
74. Elgazzar O, Eissa N, Kermarrec L, Kirouac G, Ghia JE. Irritable Bowel Syndrome-Related Neurotransmitters Transporters and Metabolism Gene Expression but Not Gut Microbiota are altered in a Rat Model of Post-Traumatic Stress Disorder Neurogastroenterology and Motility 2018; in press
75. Eissa N*, Mesgna R, Hendy G, Bernstein CN, Ghia JE. Catestatin ameliorates intestinal inflammation by orchestrating tight junction dynamics via STAT3-dependent pathway. United European Gastroenterol. J. 2018 6 (5 suppl.): Axx, OP270
76. Diarra A*, Eissa N*, Kapoor K*, Ghia JE. Regulation of endoplasmic reticulum stress/p53-apopotitic pathways by chromofungin in the context of experimental colitis. Journal of Canadian Association of Gastroenterology 2019, 2 (2 suppl.): 203-204 A102
77. Eissa N*, Diarra A*, Bernstein CN, Ghia JE. Chromogranin-A Regulates Indirectly Epithelial Repair via the alternatively activated macrophages in colonic inflammatory states. Journal of Canadian Association of Gastroenterology 2019, 2 (2 suppl.): 86-87 A43
78. Eissa N*, Hussein H*, Kermarrec L, Bernstein CN, Ghia JE. Semaphorin -3E regulates apoptosis during the development of colonic inflammation Gastroenterology 2019, in press
76. Diarra A*, Eissa N*, Kapoor K*, Ghia JE. Chromofungin protects against DSS-induced colitis by regulating P-53 apoptotic pathway. Journal of Canadian Association of Gastroenterology 2020, 3 (1 suppl.): 84-85 A212
80. Eissa N*, Diarra A*, Hussein H*, Elgazzar O*, Bernstein CN, Ghia JE. The Lack of Chromogranin-A Modifies the Gut Microbiota composition and Regulates Experimental Colonic Inflammation Journal of Canadian Association of Gastroenterology 3, (1 suppl.): 137-138 A260